You are using an outdated browser. Please upgrade your browser to improve your experience.

PROMOGRAN™ Protease Modulating Matrix

About 3M™ Promogran™ Protease Modulating Matrix

PROMOGRAN™ Protease Modulating Matrix is comprised of a sterile, freeze dried composite of 45% oxidized regenerated cellulose (ORC) and 55% collagen.


Optimum Wound Environment
PROMOGRAN™ Matrix maintains an optimal wound healing environment. This environment is conducive to granulation tissue formation, epithelization and rapid wound healing.


PROMOGRAN™ Dressing COLLAGEN & ORC is supported by a body of clinical evidence, including 13 RCT’s data. Several RCT’s have demonstrated that PROMOGRAN™ Protease Modulating Dressing achieved superior results versus standard of care in chronic wounds.


Indications for use
PROMOGRAN™ Matrix is intended for the management of all wounds healing by secondary intent which are clear of necrotic tissue, including:

  • Diabetic ulcers
  • Venous ulcers
  • Pressure ulcers
  • Ulcers caused by mixed vascular aetiologies
  • Traumatic and surgical wounds


PROMOGRAN™ Matrix can be used under compression therapy


PROMOGRAN™ Matrix is contraindicated in patients with known hypersensitivity to the components of this product, i.e. ORC and Collagen. Discontinue use if signs of sensitivity appear.

How it works

Maintains an optimum wound healing environment
In the presence of exudate, PROMOGRAN™ Matrix transforms into a soft, conformable, biodegradable gel. This allows contact with all areas of the wound.


Economic Value
An additional retrospective study analyzing cost-effectiveness in the management of neuropathic DFU (n=40), showed that wound Management with PROMOGRAN™ Matrix was more cost-effective per patient over 6 weeks of treatment as compared to standard care (Control).

Video instructions
About 3M™ Promogran™ Protease Modulating Matrix



Cookie and Privacy Statement

We use cookies to improve the functionality of our website. The data is collected completely anonymously..Want to know more? Check our Cookie and Privacy Statement