PROMOGRAN™ Protease Modulating Matrix
PROMOGRAN™ Protease Modulating Matrix is comprised of a sterile, freeze dried composite of 45% oxidized regenerated cellulose (ORC) and 55% collagen.
Optimum Wound Environment
PROMOGRAN™ Matrix maintains an optimal wound healing environment. This environment is conducive to granulation tissue formation, epithelization and rapid wound healing.
PROMOGRAN™ Dressing COLLAGEN & ORC is supported by a body of clinical evidence, including 13 RCT’s data. Several RCT’s have demonstrated that PROMOGRAN™ Protease Modulating Dressing achieved superior results versus standard of care in chronic wounds.
Indications for use
PROMOGRAN™ Matrix is intended for the management of all wounds healing by secondary intent which are clear of necrotic tissue, including:
- Diabetic ulcers
- Venous ulcers
- Pressure ulcers
- Ulcers caused by mixed vascular aetiologies
- Traumatic and surgical wounds
PROMOGRAN™ Matrix can be used under compression therapy
PROMOGRAN™ Matrix is contraindicated in patients with known hypersensitivity to the components of this product, i.e. ORC and Collagen. Discontinue use if signs of sensitivity appear.
Maintains an optimum wound healing environment
In the presence of exudate, PROMOGRAN™ Matrix transforms into a soft, conformable, biodegradable gel. This allows contact with all areas of the wound.
An additional retrospective study analyzing cost-effectiveness in the management of neuropathic DFU (n=40), showed that wound Management with PROMOGRAN™ Matrix was more cost-effective per patient over 6 weeks of treatment as compared to standard care (Control).
- Health economic burden that different wound types impose on the UK’s National Health Service
- Prospective and randomized evaluation of the protease-modulating effect of oxidised regenerated cellulose/collagen matrix treatment in Pressure sore ulcers.
- Collagen-based wound dressings for the treatment of diabetes-related foot ulcers: a systematic review.
- Use of a protease modulating matrix in the treatment of pressure sores.
- Randomized comparative trial of a collagen/oxidized regenerated cellulose dressing in the treatment of neuropathic diabetic foot ulcers.